GESearch: An Interactive GUI Tool for Identifying Gene Expression Signature

GESearch: An Interactive GUI Tool for Identifying Gene Expression Signature

The huge amount of gene expression data generated by microarray and next-generation sequencing technologies present challenges to exploit their biological meanings. When searching for the coexpression genes, the data mining process is largely affected by selection of algorithms. Thus, it is highly desirable to provide multiple options of algorithms in the user-friendly analytical toolkit to exp...

An Interactive GUI Tool for Radiotherapy Treatment Planning

Identifying a gene expression signature of cluster headache in blood

Cluster headache is a relatively rare headache disorder, typically characterized by multiple daily, short-lasting attacks of excruciating, unilateral (peri-)orbital or temporal pain associated with autonomic symptoms and restlessness. To better understand the pathophysiology of cluster headache, we used RNA sequencing to identify differentially expressed genes and pathways in whole blood of pat...

ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence

MOTIVATION Scientists and regulators are often faced with complex decisions, where use of scarce resources must be prioritized using collections of diverse information. The Toxicological Prioritization Index (ToxPi™) was developed to enable integration of multiple sources of evidence on exposure and/or safety, transformed into transparent visual rankings to facilitate decision making. The ranki...

GUInform: Interactive Fiction for GUI Prototyping

There are many methods of rapidly prototyping a graphical user interface (GUI), the most prominent being paper prototyping and wireframe prototyping. In paper prototyping, the developer creates a physical GUI prototype using simple materials such as paper, pencils, and tabbed cards. Paper prototyping, while easy to implement, leads to unrealistic and awkward user interaction. Wireframe prototyp...